Senkirkine
Senkirkine structure
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Common Name | Senkirkine | ||
|---|---|---|---|---|
| CAS Number | 2318-18-5 | Molecular Weight | 365.42100 | |
| Density | 1.22g/cm3 | Boiling Point | 604.9ºC at 760 mmHg | |
| Molecular Formula | C19H27NO6 | Melting Point | 198ºC | |
| MSDS | Chinese USA | Flash Point | 319.6ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of SenkirkineSenkirkin, a pyrrolizidine alkaloid, occured in the aerial parts of the medicinal plant Tussilago farfara, could induce chromosome damage in human lymphocytes[1]. |
| Name | senkirkin |
|---|---|
| Synonym | More Synonyms |
| Description | Senkirkin, a pyrrolizidine alkaloid, occured in the aerial parts of the medicinal plant Tussilago farfara, could induce chromosome damage in human lymphocytes[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.22g/cm3 |
|---|---|
| Boiling Point | 604.9ºC at 760 mmHg |
| Melting Point | 198ºC |
| Molecular Formula | C19H27NO6 |
| Molecular Weight | 365.42100 |
| Flash Point | 319.6ºC |
| Exact Mass | 365.18400 |
| PSA | 93.14000 |
| LogP | 0.94740 |
| Vapour Pressure | 3.72E-17mmHg at 25°C |
| Index of Refraction | 1.546 |
| Storage condition | ?20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | UN 1544 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
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Diversity of pyrrolizidine alkaloids in native and invasive Senecio pterophorus (Asteraceae): implications for toxicity.
Phytochemistry 108 , 137-46, (2014) Changes in plant chemical defenses after invasion could have consequences on the invaded ecosystems by modifying the interactions between plants and herbivores and facilitating invasion success. Howev... |
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Determination of senkirkine and senecionine in Tussilago farfara using microwave-assisted extraction and pressurized hot water extraction with liquid chromatography tandem mass spectrometry.
Talanta 79(2) , 539-46, (2009) Tussilago farfara (Kuan Donghua) is an important Chinese herbal medicine which has been shown to contain many bioactive compounds and widely used to relieve cough and resolve phlegm. However, besides ... |
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Interplant alkaloid variation and Senecio vernalis toxicity in cattle.
Vet. Hum. Toxicol. 43(3) , 147-51, (2001) Senecio vernalis and other plants containing pyrrolizidine alkaloids (PA) are implicated in the poisoning of cattle. The liver is a known target organ. In this study the content of the alkaloids senec... |
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