VH 032 amide-PEG2-amine
Modify Date: 2024-01-14 09:25:40
VH 032 amide-PEG2-amine structure
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Common Name | VH 032 amide-PEG2-amine | ||
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| CAS Number | 2341796-76-5 | Molecular Weight | 648.64 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H43Cl2N5O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VH 032 amide-PEG2-amine(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1]. |
| Name | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride |
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| Description | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
VHL |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C28H43Cl2N5O6S |
|---|---|
| Molecular Weight | 648.64 |
| Hazard Codes | Xi |
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