(S,R,S)-AHPC-C8-NH2 dihydrochloride

Modify Date: 2024-04-05 14:51:02

(S,R,S)-AHPC-C8-NH2 dihydrochloride structure	Common Name	(S,R,S)-AHPC-C8-NH2 dihydrochloride
	CAS Number	2341796-80-1	Molecular Weight	658.72
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₄₉Cl₂N₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (S,R,S)-AHPC-C8-NH2 dihydrochloride

(S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].

Name	(S,R,S)-AHPC-C8-NH2 dihydrochloride

Description	(S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. [1].Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

Molecular Formula	C₃₁H₄₉Cl₂N₅O₄S
Molecular Weight	658.72

Hazard Codes	Xi

(S,R,S)-AHPC-C8-NH2 dihydrochloride

Use of (S,R,S)-AHPC-C8-NH2 dihydrochloride

Names

(S,R,S)-AHPC-C8-NH2 dihydrochloride Biological Activity

Chemical & Physical Properties

Safety Information