Thalidomide 4'-ether-alkylC2-amine hydrochloride

Modify Date: 2024-01-11 11:08:11

Thalidomide 4'-ether-alkylC2-amine hydrochloride Structure
Thalidomide 4'-ether-alkylC2-amine hydrochloride structure
Common Name Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS Number 2341840-99-9 Molecular Weight 353.76
Density N/A Boiling Point N/A
Molecular Formula C15H16ClN3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide 4'-ether-alkylC2-amine hydrochloride


Pomalidomide-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology[1].

 Names

Name Pomalidomide-PEG1-NH2 hydrochloride

  Biological Activity

Description Pomalidomide-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology[1].
Related Catalog
Target

Cereblon

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556.

 Chemical & Physical Properties

Molecular Formula C15H16ClN3O5
Molecular Weight 353.76

 Safety Information

Hazard Codes Xi
Top Suppliers:I want be here

No recommended suppliers.


Get all suppliers and price by the below link:

Thalidomide 4'-ether-alkylC2-amine hydrochloride suppliers

Thalidomide 4'-ether-alkylC2-amine hydrochloride price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3