Irisolidone
Irisolidone structure
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Common Name | Irisolidone | ||
|---|---|---|---|---|
| CAS Number | 2345-17-7 | Molecular Weight | 314.28900 | |
| Density | 1.402g/cm3 | Boiling Point | 565.5ºC at 760mmHg | |
| Molecular Formula | C17H14O6 | Melting Point | 192 ºC (methanol ) | |
| MSDS | N/A | Flash Point | 212.3ºC | |
Use of IrisolidoneIrisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade[1][2][3]. |
| Name | 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)chromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade[1][2][3]. |
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| Related Catalog | |
| In Vitro | Irisolidone shows the high efficacy for Volume-regulated anion channels (VRAC) blockade with an IC50 of 9.8 μM in HEK293 cells[3]. Irisolidone can inhibit endothelial cell proliferation[3]. |
| References |
| Density | 1.402g/cm3 |
|---|---|
| Boiling Point | 565.5ºC at 760mmHg |
| Melting Point | 192 ºC (methanol ) |
| Molecular Formula | C17H14O6 |
| Molecular Weight | 314.28900 |
| Flash Point | 212.3ºC |
| Exact Mass | 314.07900 |
| PSA | 89.13000 |
| LogP | 2.88840 |
| Vapour Pressure | 2.15E-13mmHg at 25°C |
| Index of Refraction | 1.645 |
| Storage condition | 2-8℃ |
| Water Solubility | Practically insoluble (0.05 g/L) (25 ºC) |
| HS Code | 2914509090 |
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Irisolidone CAS#:2345-17-7 |
| Literature: Horie, Tokunaru; Shibata, Kenichi; Yamashita, Kazuyo; Fujii, Kenichi; Tsukayama, Masao; Ohtsuru, Yoshizumi Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 222 - 230 |
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Irisolidone CAS#:2345-17-7 |
| Literature: Mannich et al. Archiv der Pharmazie (Weinheim, Germany), 1937 , vol. 275, p. 317,326 |
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Irisolidone CAS#:2345-17-7 |
| Literature: Horie, Tokunaru; Shibata, Kenichi; Yamashita, Kazuyo; Fujii, Kenichi; Tsukayama, Masao; Ohtsuru, Yoshizumi Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 222 - 230 |
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Irisolidone CAS#:2345-17-7 |
| Literature: Horie, Tokunaru; Shibata, Kenichi; Yamashita, Kazuyo; Fujii, Kenichi; Tsukayama, Masao; Ohtsuru, Yoshizumi Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 222 - 230 |
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~%
Irisolidone CAS#:2345-17-7 |
| Literature: Mannich et al. Archiv der Pharmazie (Weinheim, Germany), 1937 , vol. 275, p. 317,326 |
CAS#:548-77-6
CAS#:13539-26-9
CAS#:4332-73-4| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
| Irisolidone |
| 4',6-dimethoxy-5,7-dihydroxyisoflavone |
| 5,7-dihydroxy-6,4'-dimethoxyisoflavone |
| 4'-O-Methyltectorigenin |
| 4'-methoxytectorigenin |