dMCL1-2

Modify Date: 2024-01-16 18:05:11

dMCL1-2 structure	Common Name	dMCL1-2
	CAS Number	2351218-88-5	Molecular Weight	1163.30
	Density	1.43±0.1 g/cm3(Predicted)	Boiling Point	N/A
	Molecular Formula	C₆₁H₆₆N₁₀O₁₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of dMCL1-2

dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1[1].

Name	dMCL1-2

Description	dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC
Target	KD: 30 nM (MCL1)[1]
References	[1]. Papatzimas JW, et al. From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1). J Med Chem. 2019 Jun 13;62(11):5522-5540.

Density	1.43±0.1 g/cm3(Predicted)
Molecular Formula	C₆₁H₆₆N₁₀O₁₂S
Molecular Weight	1163.30

Henan Tianfu Chemical Co., Ltd.
China
Product Name: dMCL1-2
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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dMCL1-2

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