DBCO-PEG5-DBCO

Modify Date: 2025-08-27 12:04:31

DBCO-PEG5-DBCO structure	Common Name	DBCO-PEG5-DBCO
	CAS Number	2363130-04-3	Molecular Weight	854.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₅₄N₄O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DBCO-PEG5-DBCO

DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG5-DBCO

Description	DBCO-PEG5-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₀H₅₄N₄O₉
Molecular Weight	854.99
InChIKey	SKXBZFNMPUFHFH-UHFFFAOYSA-N
SMILES	O=C(CCOCCOCCOCCOCCOCCC(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc21)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc21

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DBCO-PEG5-DBCO
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Purity: 95.0%
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