DBCO-NHCO-PEG5-NHS ester

Modify Date: 2023-01-16 13:33:05

DBCO-NHCO-PEG5-NHS ester Structure
DBCO-NHCO-PEG5-NHS ester structure
Common Name DBCO-NHCO-PEG5-NHS ester
CAS Number 1378531-80-6 Molecular Weight 693.74012
Density N/A Boiling Point N/A
Molecular Formula C36H43N3O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-NHCO-PEG5-NHS ester


DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG5-NHS ester
Synonym More Synonyms

 DBCO-NHCO-PEG5-NHS ester Biological Activity

Description DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C36H43N3O11
Molecular Weight 693.74012

 Synonyms

MFCD28334547
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