PD-L1 inhibitor 4
Modify Date: 2024-09-13 05:55:26
PD-L1 inhibitor 4 structure
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Common Name | PD-L1 inhibitor 4 | ||
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| CAS Number | 2375674-19-2 | Molecular Weight | 892.966 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C50H48N6O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PD-L1 inhibitor 4PD-L1 inhibitor 4 is a small molecule inhibitor of PD-1/PD-L1 with SPR KD of 0.079 nM.PD-L1 inhibitor 4 exhibited substantially increased binding affinity to hPD-L1, as well as PD-1/PD-L1 inhibitory activity in physiological conditions.PD-L1 inhibitor 4 also showed a dose-dependent increase in IFN-γ secretion levels in a mixed lymphocyte reaction assay. |
| Name | PD-L1 inhibitor 4 |
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| Description | PD-L1 inhibitor 4 is a small molecule inhibitor of PD-1/PD-L1 with SPR KD of 0.079 nM.PD-L1 inhibitor 4 exhibited substantially increased binding affinity to hPD-L1, as well as PD-1/PD-L1 inhibitory activity in physiological conditions.PD-L1 inhibitor 4 also showed a dose-dependent increase in IFN-γ secretion levels in a mixed lymphocyte reaction assay. |
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| References | 1. Kawashita S, et al. Bioorg Med Chem Lett. 2019 Sep 1;29(17):2464-2467. |
| Molecular Formula | C50H48N6O10 |
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| Molecular Weight | 892.966 |