Drospirenone-d4

Modify Date: 2024-01-10 21:27:05

Drospirenone-d4 structure	Common Name	Drospirenone-d4
	CAS Number	2376035-94-6	Molecular Weight	370.52
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₆D₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Drospirenone-d4

Drospirenone-d4 (Dihydrospirorenone-d4) is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone[1][2].

Name	Drospirenone-d4

Description	Drospirenone-d4 (Dihydrospirorenone-d4) is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone[1][2].
Related Catalog	Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Fuhrmann, U., et al., The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential. Contraception, 1996. 54(4): p. 243-51. [3]. Muhn, P., et al., Drospirenone: a novel progestogen with antimineralocorticoid and antiandrogenic activity. Pharmacological characterization in animal models. Contraception, 1995. 51(2): p. 99-110. [4]. Warming, L., et al., Safety and efficacy of drospirenone used in a continuous combination with 17beta-estradiol for prevention of postmenopausal osteoporosis. Climacteric, 2004. 7(1): p. 103-11.

Molecular Formula	C₂₄H₂₆D₄O₃
Molecular Weight	370.52