CC-99282

Modify Date: 2024-01-02 16:54:13

CC-99282 structure	Common Name	CC-99282
	CAS Number	2379572-34-4	Molecular Weight	535.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₀FN₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CC-99282

CC-99282 is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). CC-99282 co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. CC-99282 can be used for researching non-Hodgkin lymphomas[1].

Name	CC-99282

Description	CC-99282 is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). CC-99282 co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. CC-99282 can be used for researching non-Hodgkin lymphomas[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	Cereblon
References	[1]. J.-M. Michot, et al. A PHASE 1, MULTICENTER, OPEN-LABEL STUDY OF CC-99282 ALONE AND IN COMBINATION WITH RITUXIMAB IN PATIENTS WITH RELAPSED OR REFRACTORY NON-HODGKIN LYMPHOMAS. Hematological Oncology. Volume 39, Issue S2, Jun. 2021.

Molecular Formula	C₂₈H₃₀FN₅O₅
Molecular Weight	535.57
Storage condition	-20°C

CC-99282

Use of CC-99282

Names

CC-99282 Biological Activity

Chemical & Physical Properties