PPARγ agonist 4

Modify Date: 2025-10-07 16:28:51

PPARγ agonist 4 Structure
PPARγ agonist 4 structure
Common Name PPARγ agonist 4
CAS Number 2380227-06-3 Molecular Weight 387.45
Density N/A Boiling Point N/A
Molecular Formula C24H22FN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PPARγ agonist 4


PPARγ agonist 4 (Compound 18b) is a potent and selective agonist of PPARγ. PPARγ agonist 4 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 4 exerts antitumor potency only in combination with Imatinib[1].

 Names

Name PPARγ agonist 4

 PPARγ agonist 4 Biological Activity

Description PPARγ agonist 4 (Compound 18b) is a potent and selective agonist of PPARγ. PPARγ agonist 4 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 4 exerts antitumor potency only in combination with Imatinib[1].
Related Catalog
References

[1]. Schoepf AM, et al. Overcoming imatinib resistance in chronic myelogenous leukemia cells using non-cytotoxic cell death modulators. Eur J Med Chem. 2020 Jan 1;185:111748.

 Chemical & Physical Properties

Molecular Formula C24H22FN3O
Molecular Weight 387.45
InChIKey DSWTXSDWPPFUCE-UHFFFAOYSA-N
SMILES CCCc1nc2c(F)cccc2n1Cc1ccc(-c2ccccc2C(N)=O)cc1
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