Nile Blue chloride

Modify Date: 2024-01-09 16:51:06

Nile Blue chloride Structure
Nile Blue chloride structure
Common Name Nile Blue chloride
CAS Number 2381-85-3 Molecular Weight 353.84500
Density N/A Boiling Point 487.9ºC at 760mmHg
Molecular Formula C20H20ClN3O Melting Point >250°C
MSDS Chinese Flash Point 248.8ºC
Purity Quantity Budget Inquiry

 Use of Nile Blue chloride


Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics[1][2].

 Names

Name nile blue A
Synonym More Synonyms

 Nile Blue chloride Biological Activity

Description Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics[1][2].
Related Catalog
References

[1]. QM Ali, et al. Z-scan determination of the third-order optical nonlinearity of organic dye nile blue chloride. Modern Physics Letters B. 2006, 623-632.

[2]. Martinez V, et al. Nile Red and Nile Blue: Applications and Syntheses of Structural Analogues. Chemistry. 2016 Sep 19;22(39):13764-13782.

 Chemical & Physical Properties

Boiling Point 487.9ºC at 760mmHg
Melting Point >250°C
Molecular Formula C20H20ClN3O
Molecular Weight 353.84500
Flash Point 248.8ºC
Exact Mass 353.12900
PSA 55.06000
LogP 1.06520
Water Solubility Solubility Soluble in water, ethanol

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ1930000
CHEMICAL NAME :
Benzo(a)phenoxazin-7-ium, 5-amino-9-(diethylamino)-, chloride
CAS REGISTRY NUMBER :
2381-85-3
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H20-N3-O.Cl
MOLECULAR WEIGHT :
353.88
WISWESSER LINE NOTATION :
T D6 B666 CN JOJ GN2&2 MZ &G &15/28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
33 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
1 ppm
REFERENCE :
POASAD Proceedings of the Oklahoma Academy of Science. (Oklahoma Academy of Science, c/o Executive Secretary-Treasurer, Southwestern Oklahoma State Univ., Weatherford, OK 73096) V.1- 1910/1920- Volume(issue)/page/year: 34,114,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4350 No. of Facilities: 71 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3549 (estimated) No. of Female Employees: 1329 (estimated)

 Safety Information

Hazard Codes Xi
Safety Phrases S22-S24/25
WGK Germany 3
RTECS DJ1930000

 Synthetic Route

Total: 1 Page

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Nile Blue chloride Structure

Nile Blue chloride

CAS#:2381-85-3

Literature: DE74391 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 382

~%

Nile Blue chloride Structure

Nile Blue chloride

CAS#:2381-85-3

Literature: DE45268 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 2, p. 174 Justus Liebigs Annalen der Chemie, , vol. 289, p. 94

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Nile Blue chloride Structure

Nile Blue chloride

CAS#:2381-85-3

Literature: Helvetica Chimica Acta, , vol. 9, p. 872

 Synonyms

NILE BLUE CHLORIDE
EINECS 219-181-4
Nile Blue BX
nilebluebase
cresolfastviolet
nile blue B
nileblueax
BASIC BLUE 12
Nile Blue A
5-amino-9-diethylamino-benzo[a]phenoxazin-5-ylium,chloride
MFCD00011936
NILE BLUE A CHLORIDE
c.i.basicblue12
5-amino-9-diethylamino-benzo[a]phenoxazinylium,chloride
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