1,3-Dioxolane,2-(4-nitrophenyl)-

Modify Date: 2024-01-10 09:05:39

1,3-Dioxolane,2-(4-nitrophenyl)- Structure
1,3-Dioxolane,2-(4-nitrophenyl)- structure
Common Name 1,3-Dioxolane,2-(4-nitrophenyl)-
CAS Number 2403-53-4 Molecular Weight 195.17200
Density 1.329g/cm3 Boiling Point 332.9ºC at 760mmHg
Molecular Formula C9H9NO4 Melting Point 92 °C
MSDS N/A Flash Point 164.7ºC

 Names

Name 2-(4-nitrophenyl)-1,3-dioxolane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.329g/cm3
Boiling Point 332.9ºC at 760mmHg
Melting Point 92 °C
Molecular Formula C9H9NO4
Molecular Weight 195.17200
Flash Point 164.7ºC
Exact Mass 195.05300
PSA 64.28000
LogP 2.16340
Vapour Pressure 0.000273mmHg at 25°C
Index of Refraction 1.568

 MSDS

Version 1.1
Regulation (EC) No 1907/2006

1 - Product and Company Information

Product Name2-(4-NITROPHENYL)-1,3-DIOXOLANE-25MG

2 - Hazards Identification

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Irritating to respiratory system and skin.

3 - Composition/Information on Ingredients

Product NameCAS #EC noAnnex I
Index Number
2-(4-NITROPHENYL)-1,3-DIOXOLANE NoneNoneNone
FormulaC9H9NO4
Molecular Weight 195,1700 AMU
SynonymsRCL Substance

4 - First Aid Measures

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

5 - Fire Fighting Measures

EXTINGUISHING MEDIA
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Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

6 - Accidental Release Measures

PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
ADDITIONAL INFORMATION
Avoid contact with eyes, skin, and clothing.

7 - Handling and Storage

HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

8 - Exposure Controls / Personal Protection

ENGINEERING CONTROLS
Mechanical exhaust required. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US)
or CEN (EU). Where risk assessment shows air-purifying respirators
are appropriate use a full-face respirator with multi-purpose
combination (US) or type ABEK (EN 14387) respirator cartridges as
a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

9 - Physical and Chemical Properties

AppearancePhysical State: Liquid
PropertyValueAt Temperature or Pressure
pHN/A
BP/BP RangeN/A
MP/MP RangeN/A
Flash PointN/A
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FlammabilityN/A
Autoignition TempN/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion LimitsN/A
Vapor PressureN/A
Partition Coefficient Log Kow: 0,948
ViscosityN/A
Vapor DensityN/A
Saturated Vapor Conc. N/A
Evaporation RateN/A
Bulk DensityN/A
Decomposition Temp.N/A
Solvent ContentN/A
Water ContentN/A
Surface TensionN/A
ConductivityN/A
Miscellaneous DataN/A
SolubilityN/A

10 - Stability and Reactivity

STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide,
and nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

11 - Toxicological Information

SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.

12 - Ecological Information

No data available.

13 - Disposal Considerations

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.

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14 - Transport Information

RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.

15 - Regulatory Information

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xi
Irritant.
R-PHRASES: 37/38
Irritating to respiratory system and skin.
S-PHRASES: 23-36/37/39
Do not breathe vapor. Wear suitable protective clothing,
gloves, and eye/face protection.
Caution: Substance not yet fully tested (EU).

16 - Other Information

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2010 Co. License granted to make
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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 Safety Information

HS Code 2932999099

 Synthetic Route

~97%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Literature: Yang, Ting; Liu, Qian; Cheng, Yaobang; Cai, Wei; Ma, Yingli; Yang, Liuqing; Wu, Qianqian; Orband-Miller, Lisa A.; Zhou, Ling; Xiang, Zhijun; Huxdorf, Melanie; Zhang, Wei; Zhang, Jing; Xiang, Jia-Ning; Leung, Stewart; Qiu, Yang; Zhong, Zhong; Elliott, John D.; Lin, Xichen; Wang, Yonghui ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 1 p. 65 - 68

~92%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Literature: Arterburn, Jeffrey B.; Perry, Marc C. Organic Letters, 1999 , vol. 1, # 5 p. 769 - 771

~93%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Literature: Karimi, Babak; Seradj, Hassan; Maleki, Jafar Tetrahedron, 2002 , vol. 58, # 22 p. 4513 - 4516

~93%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Literature: Podgorski, Daniel M.; Krabbe, Scott W.; Le, Long N.; Sierszulski, Paul R.; Mohan, Ram S. Synthesis, 2010 , # 16 art. no. M01810SS, p. 2771 - 2775

~47%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Literature: Teduka, Tomomasa; Togo, Hideo Synlett, 2005 , # 6 art. no. U02605ST, p. 923 - 926

~94%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Literature: Perio, Bertrand; Dozias, Marie-Joelle; Jacquault, Patrick; Hamelin, Jack Tetrahedron Letters, 1997 , vol. 38, # 45 p. 7867 - 7870

~93%

1,3-Dioxolane,2-(4-nitrophenyl)- Structure

1,3-Dioxolane,2...

CAS#:2403-53-4

Detail
Literature: Liu, Michael T.H.; Kokosi, Joseph Heterocycles, 1985 , vol. 23, # 12 p. 3049 - 3053

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00550438