Thymidine-13C-1

Modify Date: 2024-01-18 08:16:56

Thymidine-13C-1 structure	Common Name	Thymidine-13C-1
	CAS Number	240407-53-8	Molecular Weight	243.22100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₄N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thymidine-13C-1

Thymidine-13C-1 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]

Name	1-[(2R,4S,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Description	Thymidine-13C-1 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17).;FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4

Molecular Formula	C₁₀H₁₄N₂O₅
Molecular Weight	243.22100
Exact Mass	243.09400
PSA	104.55000

Thymidine-13C-1

Use of Thymidine-13C-1

Names

Thymidine-13C-1 Biological Activity

Chemical & Physical Properties