Antituberculosis agent-2

Modify Date: 2024-01-21 13:03:56

Antituberculosis agent-2 Structure
Antituberculosis agent-2 structure
 Common Name Antituberculosis agent-2
CAS Number 2411741-01-8 Molecular Weight 323.34
Density N/A Boiling Point N/A
Molecular Formula C19H17NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antituberculosis agent-2


Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against drug-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 µg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].

 Names

Name Antituberculosis agent-2

 Antituberculosis agent-2 Biological Activity

Description Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against drug-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 µg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].
Related Catalog
References

[1]. Zhao W, et al. Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis. Eur J Med Chem. 2020 Mar 1;189:112075.

 Chemical & Physical Properties

Molecular Formula C19H17NO4
Molecular Weight 323.34
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