Antimicrobial agent-2

Modify Date: 2024-01-03 11:09:55

Antimicrobial agent-2 structure	Common Name	Antimicrobial agent-2
	CAS Number	2412592-33-5	Molecular Weight	330.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₄N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antimicrobial agent-2

Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].

Name	Antimicrobial agent-2

Description	Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS
Target	MIC: 1 μg/mL (MRSA), 2 μg/mL (Enterococcus faecalis)[1]
References	[1]. Yang XC, et al. Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents. Bioorg Chem. 2022;124:105855.

Molecular Formula	C₁₆H₁₄N₂O₄S
Molecular Weight	330.36

Antimicrobial agent-2

Use of Antimicrobial agent-2

Names

Antimicrobial agent-2 Biological Activity

Chemical & Physical Properties