HBV-IN-32

Modify Date: 2025-09-25 06:06:46

HBV-IN-32 Structure
HBV-IN-32 structure
Common Name HBV-IN-32
CAS Number 2413193-04-9 Molecular Weight 430.90
Density N/A Boiling Point N/A
Molecular Formula C22H19ClO5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HBV-IN-32


HBV-IN-32 is a potent cccDNA (covalently closed circular DNA) inhibitor. HBV-IN-32 shows anti-HBV activity with an IC50 value of 0.14 µM for HBsAg. HBV-IN-32 inhibits cell growth[1].

 Names

Name HBV-IN-32

 HBV-IN-32 Biological Activity

Description HBV-IN-32 is a potent cccDNA (covalently closed circular DNA) inhibitor. HBV-IN-32 shows anti-HBV activity with an IC50 value of 0.14 µM for HBsAg. HBV-IN-32 inhibits cell growth[1].
Related Catalog
In Vitro HBV-IN-31 (example 57) (0-50 µM; 5 days) 在 HepDES19 细胞中抑制细胞生长,IC50 为 0.09 µM[1]。 Cell Viability Assay[1] Cell Line: HepDESl9 cells Concentration: 0-50 µM Incubation Time: 5 days Result: Inhibited cell viability with an IC50 of 0.09 µM.
References

[1]. Song Feng, et al. Flavone compounds for the treatment and prophylaxis of hepatitis b virus disease. WO2020053249A1.

 Chemical & Physical Properties

Molecular Formula C22H19ClO5S
Molecular Weight 430.90
InChIKey WKZLQSHFWVBZDX-UHFFFAOYSA-N
SMILES O=C(O)C1CC(OCCOc2ccc(-c3cc(=O)c4cccc(Cl)c4s3)cc2)C1
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