HER2-IN-13

Modify Date: 2025-08-27 20:53:09

HER2-IN-13 structure	Common Name	HER2-IN-13
	CAS Number	2414056-34-9	Molecular Weight	568.96
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₃ClF₂N₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HER2-IN-13

HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1].

Name	HER2-IN-13

Description	HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	HER2:8 nM (IC50) EGFR (WT):0.40 μM (IC50) hERG:13.3 μM (IC50)
In Vitro	HER2-IN-13 (Compound 33) 抑制 hERG 通道，IC50 为 13.3 μM[1]。
References	[1]. Ding Zhou, et al. Quinazoline derivatives as antitumor agents. Patent WO2020057511A1.

Molecular Formula	C₂₆H₂₃ClF₂N₈O₃
Molecular Weight	568.96

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