Exatecan-amide-cyclopropanol

Modify Date: 2025-08-29 22:45:14

Exatecan-amide-cyclopropanol Structure
Exatecan-amide-cyclopropanol structure
Common Name Exatecan-amide-cyclopropanol
CAS Number 2414254-34-3 Molecular Weight 519.52
Density N/A Boiling Point N/A
Molecular Formula C28H26FN3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Exatecan-amide-cyclopropanol


Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent. Exatecan-amide-cyclopropanol shows anti-proliferation activity against SK-BR-3 and U87 cells, with IC50 values of 0.12 and 0.23 nM, respectively[1].

 Names

Name Exatecan-amide-cyclopropanol

 Exatecan-amide-cyclopropanol Biological Activity

Description Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent. Exatecan-amide-cyclopropanol shows anti-proliferation activity against SK-BR-3 and U87 cells, with IC50 values of 0.12 and 0.23 nM, respectively[1].
Related Catalog
References

[1]. Xu Jianyan, et al. Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof. WO2020063676A1.

 Chemical & Physical Properties

Molecular Formula C28H26FN3O6
Molecular Weight 519.52
InChIKey YBPWXIPEPLZSMS-JMQGSBJISA-N
SMILES CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(F)c(C)c3c1c2C(NC(=O)C1(O)CC1)CC3
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