c-Met-IN-10

Modify Date: 2025-08-27 22:20:19

c-Met-IN-10 Structure
c-Met-IN-10 structure
 Common Name c-Met-IN-10
CAS Number 2415291-03-9 Molecular Weight 516.48
Density N/A Boiling Point N/A
Molecular Formula C26H21FN6O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of c-Met-IN-10


c-Met-IN-10 (compound 26a) is a highly potent c-Met kinase inhibitor with an IC50 value of 16 nM. c-Met-IN-10 has inhibitory activity against cancer cells A549, H460 and HT-29 with IC50s of 0.56 ~ 1.59 μM. c-Met-IN-10 suppresses the colony formation on HT-29 cells, induces HT-29 and A549 cells apoptosis, and inhibits A549 cells motility. c-Met-IN-10 can be used for researching anticancer[1].

 Names

Name c-Met-IN-10

 c-Met-IN-10 Biological Activity

Description c-Met-IN-10 (compound 26a) is a highly potent c-Met kinase inhibitor with an IC50 value of 16 nM. c-Met-IN-10 has inhibitory activity against cancer cells A549, H460 and HT-29 with IC50s of 0.56 ~ 1.59 μM. c-Met-IN-10 suppresses the colony formation on HT-29 cells, induces HT-29 and A549 cells apoptosis, and inhibits A549 cells motility. c-Met-IN-10 can be used for researching anticancer[1].
Related Catalog
Target

c-Met:16 nM (IC50)

References

[1]. Liu J, et al. Design, synthesis and biological evaluation of novel N-[4-(2-fluorophenoxy)pyridin-2-yl]cyclopropanecarboxamide derivatives as potential c-Met kinase inhibitors. Eur J Med Chem. 2020;194:112244.

 Chemical & Physical Properties

Molecular Formula C26H21FN6O5
Molecular Weight 516.48
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Chemsrc provides c-Met-IN-10(CAS#:2415291-03-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of c-Met-IN-10 are included as well.>> amp version: c-Met-IN-10

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