JAK-IN-26

Modify Date: 2025-09-11 12:50:52

JAK-IN-26 Structure
JAK-IN-26 structure
Common Name JAK-IN-26
CAS Number 2417134-93-9 Molecular Weight 420.46
Density N/A Boiling Point N/A
Molecular Formula C22H24N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JAK-IN-26


JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].

 Names

Name JAK-IN-26

 JAK-IN-26 Biological Activity

Description JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1].
Related Catalog
References

[1]. Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29.

 Chemical & Physical Properties

Molecular Formula C22H24N6O3
Molecular Weight 420.46
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