Icosanedioic acid

Modify Date: 2025-08-25 11:00:17

Icosanedioic acid Structure
Icosanedioic acid structure
Common Name Icosanedioic acid
CAS Number 2424-92-2 Molecular Weight 342.513
Density 1.0±0.1 g/cm3 Boiling Point 504.1±23.0 °C at 760 mmHg
Molecular Formula C20H38O4 Melting Point 127ºC
MSDS N/A Flash Point 272.8±19.1 °C

 Use of Icosanedioic acid


Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

 Names

Name eicosanedioic acid
Synonym More Synonyms

 Icosanedioic acid Biological Activity

Description Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

[2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 504.1±23.0 °C at 760 mmHg
Melting Point 127ºC
Molecular Formula C20H38O4
Molecular Weight 342.513
Flash Point 272.8±19.1 °C
Exact Mass 342.277008
PSA 74.60000
LogP 7.18
Appearance of Characters Powder
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.474
Water Solubility Slightly soluble in water.

 Safety Information

Safety Phrases S22-S24/25
HS Code 2917190090

 Synthetic Route

 Customs

HS Code 2917190090
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

eicosadioic acid
Icosanedioic acid
1,18-Octadecanedicarboxylic acid
eicosa-1,20-dioic acid
eicosane diacid
1,20-icosanedioic acid
Eicossandioic acid
eicosandioic acid
Eicosanedioic acid
MFCD00059627
octadecane-1,18-dicarboxylic acid
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here





Get all suppliers and price by the below link:

Icosanedioic acid suppliers

Icosanedioic acid price

Related Compounds: More...
Icosanedioic Acid Dimethyl Ester
42235-38-1
Icosanedioic acid bis(2,3-dihydroxypropyl) ester
75569-35-6
Octanethioic acid S-propyl ester
2432-85-1
Hexanethioic acid S-decyl ester
2432-81-7
Thiopropionic acid S-undecyl ester
2432-46-4
trisporic acid
11043-91-7
Benzenesulfonic acid, 3,3-methylenebis2,4(or 4,6)-dihydroxyphenyleneazobis-, potassium sodium salt
243869-48-9
Benzoic acid, 3,4-dihydroxy-, 2-Methylpropyl ester
105603-54-1
butanedioic acid,sodium
14047-56-4
2-(cyclopropylmethyl)-3-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]propanoic acid
2171857-10-4
3-{N-benzyl-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylpentanamido}propanoic acid
2172264-54-7
6-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbut-2-enamido]-4,4-dimethylhexanoic acid
2172629-63-7
(2S)-2-[2-(cyclopropylmethyl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]propanoic acid
2648920-83-4
5-hexyl-1-methyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one
2742045-05-0
1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-4-methylpiperidine-2-carboxylic acid
2171713-79-2
2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanamido]-3,3,3-trifluoropropanoic acid
2171528-12-2
2-[3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]cyclohexane-1-carboxylic acid
2171766-29-1
1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxybutanamido]cycloheptane-1-carboxylic acid
2172058-54-5
1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxybutanoyl]-2-methylpiperidine-3-carboxylic acid
2172499-76-0