Bafisontamab

Modify Date: 2024-04-05 19:48:00

Bafisontamab structure	Common Name	Bafisontamab
	CAS Number	2437210-79-0	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	N/A	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bafisontamab

Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1].

Name	Bafisontamab

Description	Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR
Target	EGFR c-Met
In Vivo	Bafisontamab (EMB-01) 在 PDX 和 CDX 肿瘤模型中诱导的抗肿瘤活性明显强于抗 EGFR 单抗或抗 cMet 单抗。Bafisontamab 在抗 EGFR mAb 耐药肿瘤模型中表现出显著的抗肿瘤活性[1]。
References	[1]. Ren F, et al. EMB-01: An innovative bispecific antibody targeting EGFR and cMet on tumor cells mediates a novel mechanism to improve anti-tumor efficacy. Cancer Research, 2020, 80(16_Supplement): 528-528.

No Any Chemical & Physical Properties