Uridine 5′-diphosphoglucose-13C6 disodium

Modify Date: 2024-01-12 12:43:48

Uridine 5′-diphosphoglucose-13C6 disodium Structure
Uridine 5′-diphosphoglucose-13C6 disodium structure
Common Name Uridine 5′-diphosphoglucose-13C6 disodium
CAS Number 2483735-04-0 Molecular Weight 590.21
Density N/A Boiling Point N/A
Molecular Formula C913C6H19N2NaO17P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Uridine 5′-diphosphoglucose-13C6 disodium


Uridine 5′-diphosphoglucose-13C6 (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].

 Names

Name Uridine 5′-diphosphoglucose-13C6 disodium

  Biological Activity

Description Uridine 5′-diphosphoglucose-13C6 (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. DietrichKeppler, et al. Uridine-5′-diphosphoglucose. Methods of Enzymatic Analysis (Second English Edition). 1974;4:2225-2228.

[3]. Das A, et al. Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem. 2010 Jan 1453(1):471-80.  

 Chemical & Physical Properties

Molecular Formula C913C6H19N2NaO17P2
Molecular Weight 590.21