Antiparasitic agent-2

Modify Date: 2024-04-06 17:17:48

Antiparasitic agent-2 Structure
Antiparasitic agent-2 structure
Common Name Antiparasitic agent-2
CAS Number 2494277-80-2 Molecular Weight 347.37
Density N/A Boiling Point N/A
Molecular Formula C20H17N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiparasitic agent-2


Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].

 Names

Name Antiparasitic agent-2

 Antiparasitic agent-2 Biological Activity

Description Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].
Related Catalog
Target

IC50: 7.28 μM (L. infantum), 2.30 μM (T. cruzi)[1]

References

[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

 Chemical & Physical Properties

Molecular Formula C20H17N3O3
Molecular Weight 347.37
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here
Related Compounds: More...
Antiparasitic agent-8
2538594-33-9
Antiparasitic agent-6
2253996-73-3
Antiparasitic agent-5
2494276-55-8
Antiparasitic agent-9
2516237-50-4
Antiparasitic agent-10
2138480-87-0
Antiparasitic agent-7
2253996-75-5
Antiparasitic agent-4
2253996-66-4
Antiplatelet agent 2
1395047-93-4
Antimycobacterial agent-2
62670-49-9
N-(3,4-dimethylphenyl)-2-(8-methoxy-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251608-97-5
2-[3-(2-methoxyethyl)-4-oxo-7-phenyl-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-5-yl]-N-[(thiophen-2-yl)methyl]acetamide
1251634-52-2
N-(4-fluorophenyl)-2-(8-methoxy-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251579-13-1
N-(3-chloro-4-methoxyphenyl)-2-(8-methoxy-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251614-01-3
N-(3-chlorophenyl)-2-(8-methoxy-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251551-60-6
N-(2-chloro-4-methylphenyl)-2-(8-methoxy-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251609-05-8
N-(3-fluoro-4-methylphenyl)-2-(8-methyl-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251558-86-7
N-(4-chlorophenyl)-2-(8-methyl-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251550-69-2
N-(3-chloro-2-methylphenyl)-2-(8-methyl-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251635-60-5
N-(2,5-difluorophenyl)-2-(8-methyl-10-oxo-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H,5H,10H)-yl)acetamide
1251584-82-3