Antiparasitic agent-4

Modify Date: 2024-01-07 13:27:51

Antiparasitic agent-4 Structure
Antiparasitic agent-4 structure
Common Name Antiparasitic agent-4
CAS Number 2253996-66-4 Molecular Weight 279.29
Density N/A Boiling Point N/A
Molecular Formula C16H13N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiparasitic agent-4


Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].

 Names

Name Antiparasitic agent-4

 Antiparasitic agent-4 Biological Activity

Description Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].
Related Catalog
Target

IC50: 8.51 μM (L. infantum), 2.20 μM (T. cruzi)[1]

References

[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

 Chemical & Physical Properties

Molecular Formula C16H13N3O2
Molecular Weight 279.29