2253996-66-4

2253996-66-4 structure

Name: Antiparasitic agent-4
Chemical Name: Antiparasitic agent-4
CAS Number: 2253996-66-4
Molecular Formula: C₁₆H₁₃N₃O₂
Molecular Weight: 279.29
Catalog: Research Areas Infection
Create Date: 2022-07-01 19:02:15
Modify Date: 2024-01-07 13:27:51
Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].

Name	Antiparasitic agent-4

Description	Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].
Related Catalog	Research Areas >> Infection
Target	IC50: 8.51 μM (L. infantum), 2.20 μM (T. cruzi)[1]
References	[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

Molecular Formula	C₁₆H₁₃N₃O₂
Molecular Weight	279.29