Polyethylene glycol diamine

Modify Date: 2024-01-06 19:23:50

Polyethylene glycol diamine structure	Common Name	Polyethylene glycol diamine
	CAS Number	24991-53-5	Molecular Weight	1000(Average)
	Density	1.003g/cm3	Boiling Point	241ºC at 760mmHg
	Molecular Formula	(C₂H₄O)nC₄H₁₂N₂O	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	>110℃
	Symbol	GHS05, GHS08	Signal Word	Danger

Use of Polyethylene glycol diamine

PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

Name	2,2'-[1,2-Ethanediylbis(oxy)]diethanamine
Synonym	More Synonyms

Description	PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
Related Catalog	Research Areas >> Cancer
References	[1]. Han X, et al. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. Int J Pharm. 2009 May 8;372(1-2):125-31.

Density	1.003g/cm3
Boiling Point	241ºC at 760mmHg
Molecular Formula	(C₂H₄O)nC₄H₁₂N₂O
Molecular Weight	1000(Average)
Flash Point	>110℃
Exact Mass	148.12100
PSA	70.50000
LogP	0.33760
Appearance of Characters	Granular Solid \| White to off-white
Storage condition	−20°C
Water Solubility	Soluble in organic solvents. \| It is soluble in organic solvents. It is insoluble in water.

Polyethylene glycol diamine MSDS(Chinese)

Symbol	GHS05, GHS08
Signal Word	Danger
Hazard Statements	H315-H317-H318-H334
Precautionary Statements	P261-P280-P305 + P351 + P338-P342 + P311
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R36/37/38;R42/43
Safety Phrases	22-24/25-45-36/37-26
RIDADR	NONH for all modes of transport
WGK Germany	3

Synthesis of semitelechelic maleimide poly(PEGA) for protein conjugation by RAFT polymerization.

Biomacromolecules 10(7) , 1777-81, (2009)

Maleimide end functionalized polymers for site-selective conjugation to free cysteines of proteins were synthesized using reversible addition-fragmentation chain transfer (RAFT) polymerization. A fura...

Construction of highly glycosylated mucin-type glycopeptides based on microwave-assisted solid-phase syntheses and enzymatic modifications.

J. Org. Chem. 71(8) , 3051-63, (2006)

A MUC1-related glycopeptide having five core-2 hexasaccharide branches (C330H527N46O207, MW = 8450.9) was synthesized by a new strategy using a combination of microwave-assisted solid-phase synthesis ...

Solid-phase library synthesis, screening, and selection of tight-binding reduced peptide bond inhibitors of a recombinant Leishmania mexicana cysteine protease B.

J. Med. Chem. 45(10) , 1971-82, (2002)

A one-bead-two-compound inhibitor library was synthesized by the split-mix method for the identification of inhibitors of a recombinant cysteine protease from Leishmania mexicana, CPB2.8DeltaCTE. The ...

α,ω-Diamino Poly(Ethylene Glycol)

MFCD00132004

Poly(ethylene glycol) diamine

H2N-PEG-NH2

Polyethylene glycol diamine

Poly(ethylene glycol) bis(amine)