DENV-IN-7

Modify Date: 2024-04-07 19:00:22

DENV-IN-7 structure	Common Name	DENV-IN-7
	CAS Number	2499537-22-1	Molecular Weight	438.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DENV-IN-7

DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC50 value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity[1].

Name	DENV-IN-7

Description	DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC50 value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
In Vitro	DENV-IN-7 (compound 5d; 10 μM; 48 h) 对 LLC/MK2 细胞具有低毒性[1]。 DENV-IN-7 (1 nM-10 μM; 72 h) 具有抗登革热活性，并抑制 DENV2 感染的 LLC/MK2 细胞中的病毒复制[1]。 Cell Viability Assay[1] Cell Line: LLC/MK2 cells Concentration: 10 μM Incubation Time: 48 hours Result: Had non-toxic with the viability above 75%.
References	[1]. Patigo A, et, al. Design, synthesis, in vitro, in silico, and SAR studies of flavone analogs towards anti-dengue activity. Sci Rep. 2022 Dec 14;12(1):21646.

Molecular Formula	C₂₄H₂₂O₈
Molecular Weight	438.43

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