MRE 3008F20

Modify Date: 2025-08-25 12:39:27

MRE 3008F20 Structure
MRE 3008F20 structure
Common Name MRE 3008F20
CAS Number 252979-43-4 Molecular Weight 432.44
Density N/A Boiling Point N/A
Molecular Formula C21H20N8O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRE 3008F20


MRE3008F20 is a highly potent and selective antagonistic of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM[1].

 Names

Name 1-[2-(2-Furyl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]p yrimidin-5-yl]-3-(4-methoxyphenyl)ure

 MRE 3008F20 Biological Activity

Description MRE3008F20 is a highly potent and selective antagonistic of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM[1].
Related Catalog
Target

IC50 : 5 nM (AA3R, resting T lymphocytes)[1]

References

[1]. Gessi S, et al. Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation. Mol Pharmacol. 2004 Mar;65(3):711-9.

 Chemical & Physical Properties

Molecular Formula C21H20N8O3
Molecular Weight 432.44
Exact Mass 432.16600
PSA 127.63000
LogP 3.29150
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