1-(2-(trifluoromethyl)phenyl)-1h-imidazole
Modify Date: 2025-08-21 12:00:02
1-(2-(trifluoromethyl)phenyl)-1h-imidazole structure
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Common Name | 1-(2-(trifluoromethyl)phenyl)-1h-imidazole | ||
|---|---|---|---|---|
| CAS Number | 25371-96-4 | Molecular Weight | 212.171 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 288.3±40.0 °C at 760 mmHg | |
| Molecular Formula | C10H7F3N2 | Melting Point | 43 °C | |
| MSDS | USA | Flash Point | 128.2±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 1-(2-(trifluoromethyl)phenyl)-1h-imidazoleTRIM is a potent nitric oxide synthase inhibitor. TRIM inhibits mouse cerebellar nNOS and rat lung iNOS in vitro with IC50 values of 28.2 and 27.0 µM, respectively. Antidepressant- and anxiolytic-like effects[1][2]. |
| Name | 1-[2-(trifluoromethyl)phenyl]imidazole |
|---|---|
| Synonym | More Synonyms |
| Description | TRIM is a potent nitric oxide synthase inhibitor. TRIM inhibits mouse cerebellar nNOS and rat lung iNOS in vitro with IC50 values of 28.2 and 27.0 µM, respectively. Antidepressant- and anxiolytic-like effects[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | TRIM is a relatively weak inhibitor of eNOS (IC50, 1057.5 µM)[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 288.3±40.0 °C at 760 mmHg |
| Melting Point | 43 °C |
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.171 |
| Flash Point | 128.2±27.3 °C |
| Exact Mass | 212.056137 |
| PSA | 17.82000 |
| LogP | 2.55 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.522 |
| InChIKey | WZBWBNCQUTXYEL-UHFFFAOYSA-N |
| SMILES | FC(F)(F)c1ccccc1-n1ccnc1 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933290090 |
| HS Code | 2933290090 |
|---|---|
| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Tocris HTS for Inhibitors of Aerobactin Synthetase lucA
Source: 23265
External Id: IucA Pilot Assay Tocris Library
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ant...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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| 1-[2-(Trifluoromethyl)phenyl]-1H-imidazole |
| 1-(2-(trifluoromethyl)phenyl)-1h-imidazole |
| 1-[2-(Trifluoromethyl)phenyl]imidazole |
| Trim |
| MFCD00041206 |