adipic acid d-10

Modify Date: 2025-08-25 15:30:35

adipic acid d-10 Structure
adipic acid d-10 structure
Common Name adipic acid d-10
CAS Number 25373-21-1 Molecular Weight 156.203
Density 1.3±0.1 g/cm3 Boiling Point 338.5±15.0 °C at 760 mmHg
Molecular Formula C6D10O4 Melting Point 151-154ºC(lit.)
MSDS Chinese USA Flash Point 196.1±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of adipic acid d-10


Adipic acid-d10 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

 Names

Name dideuterio 2,2,3,3,4,4,5,5-octadeuteriohexanedioate
Synonym More Synonyms

 adipic acid d-10 Biological Activity

Description Adipic acid-d10 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. G.Frauendienst-Egger, Friedrich K. Trefz (2017). MetaGene: Metabolic & Genetic Information Center. METAGENE consortium.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 338.5±15.0 °C at 760 mmHg
Melting Point 151-154ºC(lit.)
Molecular Formula C6D10O4
Molecular Weight 156.203
Flash Point 196.1±0.0 °C
Exact Mass 156.120682
PSA 74.60000
LogP 0.08
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.476

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xn: Harmful;Xi: Irritant
Risk Phrases R20/22-36
Safety Phrases 26-36
WGK Germany 3

 Synonyms

Decadeuterio-adipinsaeure
Hexanedioic-d acid-d
MFCD00190459
(H)Hexane(H)dioic acid
decadeuterio-adipic acid
Deuterated adipic acid,Hexanedioic acid-d10
adipic acid d-10
decadeuterio-hexanedioic acid
adipic-d8 acid-d2
D10-adipic acid
Hexanedioic acid-d10
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