Fibrinopeptide A human structure
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Common Name | Fibrinopeptide A human | ||
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CAS Number | 25422-31-5 | Molecular Weight | 1536.56000 | |
Density | 1.53 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C63H97N19O26 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of Fibrinopeptide A humanFibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. |
Name | Fibrinopeptide A |
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Synonym | More Synonyms |
Description | Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. |
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Related Catalog | |
In Vitro | The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1]. |
In Vivo | Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. |
References |
Density | 1.53 g/cm3 |
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Molecular Formula | C63H97N19O26 |
Molecular Weight | 1536.56000 |
Exact Mass | 1535.69000 |
PSA | 731.15000 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Thromboprophylaxis in patients receiving chemotherapy.
N. Engl. J. Med. 366(19) , 1839; author reply 1839-40, (2012)
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Routine heparin for patients with cancer? One answer, more questions.
N. Engl. J. Med. 366(7) , 661-2, (2012)
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Congenital dysfibrinogenemia Aα Gly13Glu associated with bleeding during pregnancy.
Thromb. Res. 127(3) , 277-8, (2011)
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fibrinopeptide a, human |
MFCD00076437 |
ADSGEGDFLAEGGGVR |