61533-47-9
61533-47-9 structure
- Name: Fibrinopeptide A, human TFA
- Chemical Name: Fibrinopeptide A, human TFA
- CAS Number: 61533-47-9
- Molecular Formula: C67H99F6N19O30
- Molecular Weight: 1764.62
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-04-23 09:00:21
- Modify Date: 2024-01-12 04:08:21
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Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain[1].
| Name | Fibrinopeptide A, human TFA |
|---|
| Description | Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain[1]. |
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| Related Catalog | |
| In Vitro | The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1]. |
| In Vivo | Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. |
| References |
| Molecular Formula | C67H99F6N19O30 |
|---|---|
| Molecular Weight | 1764.62 |