Glyceryl monooleate

Modify Date: 2024-01-02 10:57:00

Glyceryl monooleate Structure
Glyceryl monooleate structure
Common Name Glyceryl monooleate
CAS Number 25496-72-4 Molecular Weight 356.540
Density 1.0±0.1 g/cm3 Boiling Point 483.3±35.0 °C at 760 mmHg
Molecular Formula C21H40O4 Melting Point 36 - 40ºC
MSDS N/A Flash Point 155.4±19.4 °C

 Use of Glyceryl monooleate


Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro[1][2].

 Names

Name Glycerol mono-oleate
Synonym More Synonyms

 Glyceryl monooleate Biological Activity

Description Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro[1][2].
Related Catalog
References

[1]. Milak S, et al. Glycerol monooleate liquid crystalline phases used in drug delivery systems. Int J Pharm. 2015 Jan 30;478(2):569-87.

[2]. Zhen G, et al. Glycerol monooleate-based nanocarriers for siRNA delivery in vitro. Mol Pharm. 2012 Sep 4;9(9):2450-7.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 483.3±35.0 °C at 760 mmHg
Melting Point 36 - 40ºC
Molecular Formula C21H40O4
Molecular Weight 356.540
Flash Point 155.4±19.4 °C
Exact Mass 356.292664
PSA 66.76000
LogP 6.71
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.479
Storage condition −20°C
Water Solubility chloroform: 50 mg/mL, clear, colorless

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RK1300000
CHEMICAL NAME :
Olein, mono-
CAS REGISTRY NUMBER :
25496-72-4
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H40-O4
MOLECULAR WEIGHT :
356.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83110 No. of Facilities: 4016 (estimated) No. of Industries: 41 No. of Occupations: 51 No. of Employees: 74220 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83110 No. of Facilities: 9941 (estimated) No. of Industries: 81 No. of Occupations: 78 No. of Employees: 159120 (estimated) No. of Female Employees: 39063 (estimated)

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 1

 Articles41

More Articles
Profiling of regioisomeric triacylglycerols in edible oils by supercritical fluid chromatography/tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 966 , 193-9, (2014)

In this study, supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry was applied to the profiling of several regioisomeric triacylglycerols (TAGs). SFC conditions (...

Identification of a novel hypocholesterolemic protein, major royal jelly protein 1, derived from royal jelly.

PLoS ONE 9(8) , e105073, (2014)

Royal jelly (RJ) intake lowers serum cholesterol levels in animals and humans, but the active component in RJ that lowers serum cholesterol level and its molecular mechanism are unclear. In this study...

Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination.

Cell. Mol. Life Sci. 71(24) , 4895-910, (2014)

Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big...

 Synonyms

Glyceryl cis-9-octadecenoate
9-Octadecenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (9Z)-
Oleic monoglyceride
9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol
1-monooleoyl-rac-glycerol
1-(cis-9-Octadecenoyl)-rac-glycerol
1-Monooleoylglycerol
rac-Glycerol 1-monooleate
Glycerin 1-monooleate
glycerol monooleate
rac 1-Oleoyl Glycerol
4,5-Dihydroxypentyl (7Z)-7-hexadecenoate
Glycerin monooleate
Oleic acid glycerol monoester
1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate
Glycerine monooleate
1-O-Oleyl-rac-glycerol
1-oleoyl glycerol
1-OLEOYLGLYCEROL
OLEOYL GLYCEROL
GLYCEROL OLEATE
9-Octadecenoic acid, 2,3-dihydroxypropyl ester, (9Z)-
1,3-Dihydroxy-2-propanyl (9Z)-9-octadecenoate
MFCD00042735
2,3-Dihydroxypropyl (9Z)-9-octadecenoate
2,3-Dihydroxypropyl oleate
GLYCEROL MONO-OLEATE
MONO OLEIN
Glycerine oleate
1-GLYCERYL OLEATE
Glycerol Alpha-Monooleate
GLYCERYL MONOOLEATE
2,3-Dihydroxypropyl (9Z)-octadec-9-enoate
a-Monoolein
DL-ALPHA-MONOOLEIN
Monoolein 9 C18:1
Danisco MO 90
GLYCEROL MONO OLEATE
Monoolein (VAN)
2-hydroxy-1-(hydroxymethyl)ethyl (9Z)-octadec-9-enoate
1-Oleoyl-rac-glycerol
2-Oleoylglycerol
Glyceryl Monooleate (VAN)
RAC.-1-OLEOYL-GLYCEROL BIOCHEMICA
(9Z)-9-Octadecenoic Acid 2,3-Dihydroxypropyl Ester
dl-α-Monoolein
Glycerol α-monooleate
UNII:D3AEF6S35P
α-Monoolein
rac-1-Monooleoylglycerol
7-Hexadecenoic acid, 4,5-dihydroxypentyl ester, (7Z)-
9-Octadecenoic acid (9Z)-, ester with 1,2,3-propanetriol
Monoolein
1-Mono(cis-9-octacenoyl)glycerol
EINECS 247-038-6
Aldo HMO
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