Isoferulic acid

Modify Date: 2025-08-25 12:58:44

Isoferulic acid Structure
Isoferulic acid structure
 Common Name Isoferulic acid
CAS Number 25522-33-2 Molecular Weight 194.184
Density 1.3±0.1 g/cm3 Boiling Point 410.2±35.0 °C at 760 mmHg
Molecular Formula C10H10O4 Melting Point N/A
MSDS Chinese USA Flash Point 167.6±19.4 °C

 Use of Isoferulic acid


trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[1].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[2].

 Names

Name trans-Isoferulic acid
Synonym More Synonyms

 Isoferulic acid Biological Activity

Description trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[1].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Kai-Hui Sun, et al. A new indole-type alkaloid from the roots of Clematis florida var. plena. Nat Prod Res. 2019 Oct;33(20):2925-2931.

[2]. Matharage Gayani Dilshara, et al. Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1. Int Immunopharmacol. 2014 Jan;18(1):203-11.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 410.2±35.0 °C at 760 mmHg
Molecular Formula C10H10O4
Molecular Weight 194.184
Flash Point 167.6±19.4 °C
Exact Mass 194.057907
PSA 66.76000
LogP 1.56
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.627
InChIKey QURCVMIEKCOAJU-HWKANZROSA-N
SMILES COc1ccc(C=CC(=O)O)cc1O
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Articles1

More Articles
Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC-ESI-MS/MS.

Talanta 128 , 221-30, (2014)

An increasing number of studies have concerned the profiling of polyphenol microbial metabolites, especially in urine or plasma, but only a few have regarded their accurate quantification. This study ...

 Isoferulic acidBioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Inhibition of diphenolase activity of mushroom tyrosinase at 0.035 mM
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL892362
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Total 137, Current Page 1 of 14
1
2
3
4
5

 Synonyms

trans-3-(3-Hydroxy-4-methoxyphenyl)acrylic acid trans-3-Hydroxy-4-methoxycinnamic acid
(E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid
3-(3-Hydroxy-4-methoxyphenyl)acrylic acid
Isoferulic acid
EINECS 247-071-6
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Isoferulic acid suppliers

Isoferulic acid price

Related Compounds: More...
N-{4-[(methylsulfanyl)methyl]phenyl}-1-(prop-2-enoyl)piperidine-4-carboxamide
2411253-09-1
tert-butyl N-[1-(2,2,2-trifluoro-1-hydroxyethyl)cyclopentyl]carbamate
2228378-83-2
tert-butyl N-[1-(1-aminocyclopentyl)cyclobutyl]carbamate
2229192-19-0
3-(1-Benzothiophen-3-yloxy)pyrrolidine
2228636-32-4
2-(1-Bromo-2-methylpropan-2-yl)-3-methylpyrazine
2229337-78-2
3-[(4-Methoxypiperidin-4-yl)methyl]-5-methylpyridine
2228242-08-6
Tert-butyl 2-(3-chloro-2-hydroxyphenyl)piperazine-1-carboxylate
2229622-45-9
4-(4-Ethoxy-2-methylphenyl)but-3-en-2-one
2229672-62-0
[2-(2-Fluoroethyl)cyclopropyl]methanamine
2229101-97-5
1-(2-fluoro-6-nitrophenyl)-N-methylcyclopropan-1-amine
2228378-94-5
Chemsrc provides Isoferulic acid(CAS#:25522-33-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Isoferulic acid are included as well.>> amp version: Isoferulic acid

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2026 ChemSrc All Rights Reserved