HIV-1 inhibitor-21
Modify Date: 2024-01-04 17:22:17
HIV-1 inhibitor-21 structure
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Common Name | HIV-1 inhibitor-21 | ||
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| CAS Number | 2554620-04-9 | Molecular Weight | 476.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H24N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HIV-1 inhibitor-21HIV-1 inhibitor-21 (compound 9b) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 0.55 μM for HIV-1 RT. HIV-1 inhibitor-21 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 12.7 nM and 10.4 nM, and has relatively low cytotoxicity (MT-4 cells CC50 =10.2 μM)[1]. |
| Name | HIV-1 inhibitor-21 |
|---|
| Description | HIV-1 inhibitor-21 (compound 9b) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 0.55 μM for HIV-1 RT. HIV-1 inhibitor-21 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 12.7 nM and 10.4 nM, and has relatively low cytotoxicity (MT-4 cells CC50 =10.2 μM)[1]. |
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| Related Catalog | |
| Target |
HIV-1 (WT):12.7 nM (EC50) HIV-1 (K103N):10.4 nM (EC50) |
| References |
| Molecular Formula | C28H24N6O2 |
|---|---|
| Molecular Weight | 476.53 |