VK3-OCH3
Modify Date: 2025-08-26 15:14:12
VK3-OCH3 structure
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Common Name | VK3-OCH3 | ||
|---|---|---|---|---|
| CAS Number | 255906-59-3 | Molecular Weight | 262.32400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H14O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS09 |
Signal Word | Warning | |
Use of VK3-OCH3VK3-OCH3 is a potent antitumor agent. VK3-OCH3 shows cytotoxicity for neuroblastoma cell lines and low cytotoxicity for normal cell lines. VK3-OCH3 induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells. VK3-OCH3 shows antitumor activity[1]. |
| Name | 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-naphthoquinone |
|---|---|
| Synonym | More Synonyms |
| Description | VK3-OCH3 is a potent antitumor agent. VK3-OCH3 shows cytotoxicity for neuroblastoma cell lines and low cytotoxicity for normal cell lines. VK3-OCH3 induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells. VK3-OCH3 shows antitumor activity[1]. |
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| Related Catalog | |
| In Vitro | VK3-OCH3 (compound 5) shows cytotoxicity with IC50s of 2.43, 1.55, 10.69, 3.45, 26.24, 87.11 µM for IMR-32, LA-N-1, NB-39, SK-N-SH, HUVEC, HDF cells, respectively[1]. VK3-OCH3 (1, 3, 10 µM) induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells[1]. VK3-OCH3 (0-48 h) increases the expression of HO-1 in 8~24 h, and Caveolin-1 in 48 h in IMR-32 and LA-N-1 cells[1]. VK3-OCH3 (0-48 h) increases the expression of phospho-p38-MAPK and decreases the expression of p21 and clusterin[1]. |
| References |
| Molecular Formula | C14H14O3S |
|---|---|
| Molecular Weight | 262.32400 |
| Exact Mass | 262.06600 |
| PSA | 68.67000 |
| LogP | 2.71920 |
| Storage condition | 2-8°C |
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| 2-[(2-Methoxyethyl)thio]-3-methyl-1,4-napthalenedione |
| 2-(2-methoxyethylsulfanyl)-3-methylnaphthalene-1,4-dione |