BAY 41-2272
Modify Date: 2024-01-02 16:08:58
BAY 41-2272 structure
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Common Name | BAY 41-2272 | ||
|---|---|---|---|---|
| CAS Number | 256376-24-6 | Molecular Weight | 360.388 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 496.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C20H17FN6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 253.8±28.7 °C | |
Use of BAY 41-2272BAY 41-2272 is a soluble guanylate cyclases (sGC) activator.Target: guanylate cyclaseBAY 41-2272 is a recently introduced novel orally available agent that directly stimulates soluble guanylate cyclase (sGC) and sensitizes it to its physiological stimulator, nitric oxide. BAY 41-2272 is a promising new therapeutic agent that goes beyond current therapeutic agents. BAY 41-2272 acts as an arterial vasodilator, resulting in a reduction of MAP and pulmonary artery pressure and a decrease in SVR and renal vascular resistance. BAY 41-2272 reduces pulmonary capillary wedge pressure in the absence of a decrease in right atrial pressure. [2] |
| Name | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine |
|---|---|
| Synonym | More Synonyms |
| Description | BAY 41-2272 is a soluble guanylate cyclases (sGC) activator.Target: guanylate cyclaseBAY 41-2272 is a recently introduced novel orally available agent that directly stimulates soluble guanylate cyclase (sGC) and sensitizes it to its physiological stimulator, nitric oxide. BAY 41-2272 is a promising new therapeutic agent that goes beyond current therapeutic agents. BAY 41-2272 acts as an arterial vasodilator, resulting in a reduction of MAP and pulmonary artery pressure and a decrease in SVR and renal vascular resistance. BAY 41-2272 reduces pulmonary capillary wedge pressure in the absence of a decrease in right atrial pressure. [2] |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 496.1±45.0 °C at 760 mmHg |
| Molecular Formula | C20H17FN6 |
| Molecular Weight | 360.388 |
| Flash Point | 253.8±28.7 °C |
| Exact Mass | 360.149872 |
| PSA | 83.24000 |
| LogP | 1.99 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.767 |
| Storage condition | -20℃ |
| Precursor 9 | |
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| DownStream 0 | |
CAS#:256376-79-1![1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)Methyl]- Structure](https://image.chemsrc.com/caspic/047/256376-68-8.png)
CAS#:256376-68-8
CAS#:6542-60-5
CAS#:51859-98-4![1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile Structure](https://image.chemsrc.com/caspic/161/256376-65-5.png)
CAS#:256376-65-5
CAS#:256504-39-9![1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide Structure](https://image.chemsrc.com/caspic/275/256376-62-2.png)
CAS#:256376-62-2![1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidic acid methyl ester Structure](https://image.chemsrc.com/caspic/452/304874-06-4.png)
CAS#:304874-06-4![1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester Structure](https://image.chemsrc.com/caspic/216/256376-59-7.png)
CAS#:256376-59-7| 5-Cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
| 5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine |
| 3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine |
| bay-41-2272 |
| 4-pyrimidinamine, 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]- |
| unii-34a162j6wb |
| BAY 41-2272 |