CRA-2059

Modify Date: 2025-08-26 19:17:26

CRA-2059 structure	Common Name	CRA-2059
	CAS Number	256649-36-2	Molecular Weight	750.80
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₄₆N₁₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CRA-2059

CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].

Name	CRA-2059

Description	CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Inflammation/Immunology
In Vitro	Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 has the potential for inflammatory bowel disease research[1].
References	[1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Aliment Pharmacol Ther. 2002;16(3):407-413. [2]. Selwood T, et al. Potent bivalent inhibition of human tryptase-beta by a synthetic inhibitor. Biol Chem. 2003;384(12):1605-1611.

Molecular Formula	C₃₄H₄₆N₁₂O₈
Molecular Weight	750.80

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CRA-2059
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

CRA-2059 suppliers