KTX-955

Modify Date: 2024-09-19 17:21:46

KTX-955 structure	Common Name	KTX-955
	CAS Number	2573302-50-6	Molecular Weight	884.94
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₅₁F₃N₈O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KTX-955

KTX-955 is a potent IRAK4 degrader with DC50 values of 5 nM and 130 nM for IRAK4 and Ikaros, respectively. KTX-955 can be used to research anticancer[1][2].

Name	KTX-955

Description	KTX-955 is a potent IRAK4 degrader with DC50 values of 5 nM and 130 nM for IRAK4 and Ikaros, respectively. KTX-955 can be used to research anticancer[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> IRAK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK
Target	IRAK4:5 nM (IC50)
In Vitro	KTX-955 (compound I-312) degrades IRAK4 in OCI-LY10 at 24 hours with an IC50 of <0.05 μM[1].
References	[1]. Matthew Weiss. Discovery and characterization of IRAKIMiDs: degraders targeting both IRAK4 and IMiD substrates for oncology indications. Northeastern Section, ACS (NESACS). [2]. Nello Mainolfi, et al. Irak degraders and uses thereof. WO2020264499A1

Molecular Formula	C₄₆H₅₁F₃N₈O₇
Molecular Weight	884.94

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: KTX-955
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: KTX-955
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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