KTX-955
Modify Date: 2025-08-22 16:47:25
KTX-955 structure
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Common Name | KTX-955 | ||
|---|---|---|---|---|
| CAS Number | 2573302-50-6 | Molecular Weight | 884.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C46H51F3N8O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KTX-955KTX-955 is a potent IRAK4 degrader with DC50 values of 5 nM and 130 nM for IRAK4 and Ikaros, respectively. KTX-955 can be used to research anticancer[1][2]. |
| Name | KTX-955 |
|---|
| Description | KTX-955 is a potent IRAK4 degrader with DC50 values of 5 nM and 130 nM for IRAK4 and Ikaros, respectively. KTX-955 can be used to research anticancer[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IRAK4:5 nM (IC50) |
| In Vitro | KTX-955 (compound I-312) degrades IRAK4 in OCI-LY10 at 24 hours with an IC50 of <0.05 μM[1]. |
| References |
[2]. Nello Mainolfi, et al. Irak degraders and uses thereof. WO2020264499A1 |
| Molecular Formula | C46H51F3N8O7 |
|---|---|
| Molecular Weight | 884.94 |