disperse orange 1

Modify Date: 2024-01-11 14:45:55

disperse orange 1 Structure
disperse orange 1 structure
 Common Name disperse orange 1
CAS Number 2581-69-3 Molecular Weight 318.32900
Density 1.24g/cm3 Boiling Point 535ºC at 760mmHg
Molecular Formula C18H14N4O2 Melting Point 160ºC
MSDS Chinese USA Flash Point 277.4ºC

 Use of disperse orange 1


DO1, also known as Disperse Orange 1, is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations, thereby disrupting preformed fibrillar assemblies of synthetic Aβ42 peptides.

 Names

Name 4-[(4-nitrophenyl)diazenyl]-N-phenylaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 535ºC at 760mmHg
Melting Point 160ºC
Molecular Formula C18H14N4O2
Molecular Weight 318.32900
Flash Point 277.4ºC
Exact Mass 318.11200
PSA 82.57000
LogP 6.35000
Vapour Pressure 1.6E-11mmHg at 25°C
Index of Refraction 1.642

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JJ9700000
CHEMICAL NAME :
Diphenylamine, 4-((p-nitrophenyl)azo)-
CAS REGISTRY NUMBER :
2581-69-3
BEILSTEIN REFERENCE NO. :
0758695
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C18-H14-N4-O2
MOLECULAR WEIGHT :
318.36
WISWESSER LINE NOTATION :
WNR DNUNR DMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
31 gm/kg/88W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
REFERENCE :
ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 57,530,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0746 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 741 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0754 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 741 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0754 No. of Facilities: 55 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1125 (estimated) No. of Female Employees: 78 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R36/37/38
Safety Phrases 37/39-26-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS JJ9700000
HS Code 2927000090

 Customs

HS Code 2927000090
Summary 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles6

More Articles
Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds.

Contact Dermatitis 67(3) , 130-40, (2012)

It is known that, in vitro, human skin bacteria are able to split disperse azo dyes into the corresponding aromatic amines, some of which are sensitizers in the local lymph node assay. We hypothesize ...
Chlorination treatment of aqueous samples reduces, but does not eliminate, the mutagenic effect of the azo dyes Disperse Red 1, Disperse Red 13 and Disperse Orange 1

Mutat. Res. 703(2) , 200-8, (2010)

The treatment of textile effluents by the conventional method based on activated sludge followed by a chlorination step is not usually an effective method to remove azo dyes, and can generate products...
Textile dyes Disperse Orange 1 and Yellow 3 contain more than one allergen as shown by patch testing with thin-layer chromatograms.

Dermatitis 22(6) , 335-43, (2011)

It is known that some patch-test preparations containing disperse dyes contain impurities with unknown relevance for the development or elicitation of contact allergy.To evaluate the significance of t...

 Synonyms

Disperse Orange 5R
EINECS 219-954-6
4-(4-Nitrophenylazo)diphenylamine
Vonteryl Red 4G
Acetate Orange 5R
Resolin Orange 5R
4-[(4-nitrophenyl)azo]-N-phenyl-benzenamine
Miketon Fast Orange 5R
[4-(4-nitro-phenylazo)-phenyl]-phenyl-amine
Palanil Orange 5R
(4-Nitro-benzol)-(1 azo 4)-N.N-diphenylamin
4-nitro-4'-phenylaminoazobenzene
Reliton Orange 5R
Disperse Orange 1
[4-(4-Nitro-phenylazo)-phenyl]-phenyl-amin
Dispersol Orange A
4'-Nitro-4-anilino-azobenzol
Serisol Orange 5R
MFCD00007311
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Related Compounds: More...
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Chemsrc provides disperse orange 1(CAS#:2581-69-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of disperse orange 1 are included as well.>> amp version: disperse orange 1

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