Fosfomycin calcium structure
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Common Name | Fosfomycin calcium | ||
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CAS Number | 26016-98-8 | Molecular Weight | 176.121 | |
Density | N/A | Boiling Point | 342.7ºC at 760 mmHg | |
Molecular Formula | C3H5CaO4P | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 161ºC |
Use of Fosfomycin calciumFosfomycin calcium is an antibiotics, used in urinary tract infections and intestinal infections caused by susceptible strains. |
Name | Phosphomycin calcium salt |
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Synonym | More Synonyms |
Description | Fosfomycin calcium is an antibiotics, used in urinary tract infections and intestinal infections caused by susceptible strains. |
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Related Catalog |
Boiling Point | 342.7ºC at 760 mmHg |
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Molecular Formula | C3H5CaO4P |
Molecular Weight | 176.121 |
Flash Point | 161ºC |
Exact Mass | 175.955139 |
PSA | 85.53000 |
LogP | 0.78530 |
Material Safety Data Sheet
Section1. Identification of the substance Product Name: Fosfomycin calcium monohydrate Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Fosfomycin calcium monohydrate CAS number:26016-98-8 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C3H5O4P.Ca.H2O Molecular weight:194.1 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xn |
RIDADR | NONH for all modes of transport |
WGK Germany | 2 |
RTECS | SZ7895000 |
HS Code | 2942000000 |
HS Code | 2931900090 |
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Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
Antibacterial activities of a fosfomycin/tobramycin combination: a novel inhaled antibiotic for bronchiectasis.
J. Antimicrob. Chemother. 64 , 829-836, (2009) To compare the in vitro and in vivo activities of a 4:1 (w/w) fosfomycin/tobramycin combination (FTI) with those of fosfomycin and tobramycin alone against cystic fibrosis (CF) and non-CF bronchiectas... |
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Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis.
Microbiology 145 , 3177-3184, (1999) Mycobacterium tuberculosis has innate resistance to a range of broad-spectrum antimicrobial agents. This may in part reflect the relative impermeability of the mycobacterial cell wall, but additional ... |
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FosB, a cysteine-dependent fosfomycin resistance protein under the control of sigma(W), an extracytoplasmic-function sigma factor in Bacillus subtilis.
J. Bacteriol. 183 , 2380-2383, (2001) We demonstrate that the Bacillus subtilis fosB(yndN) gene encodes a fosfomycin resistance protein. Expression of fosB requires sigma(W), and both fosB and sigW mutants are fosfomycin sensitive. FosB i... |
MFCD00242804 |
phosphomycincalcium |
PHOSPHOMYCIN |
calciumphosphonomycin |
Fosfomycin calcium |
[(3-Methyl-2-oxiranyl)phosphonato(2-)-κO,O']calcium |
Harosmin-S |
calciumphosphomycin |
Phosphomycin calcium |
Calcium [(2R,3S)-3-methyl-2-oxiranyl]phosphonate |
Clulolaxin |
Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1) |
Fosfomycin caclium(+/-) |
Fosfomycin calcium salt |
fosmicin |
Calcium, [phosphonato(2-)-κO,κO', (3-methyloxiranyl)-]- |
calciumfosfomycin |
calcium [(2R,3S)-3-methyloxiran-2-yl]phosphonate |
EINECS 247-408-7 |
Fosfomycin (calcium) |