CGS 35066

Modify Date: 2024-01-13 17:29:05

CGS 35066 structure	Common Name	CGS 35066
	CAS Number	261619-50-5	Molecular Weight	349.27500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₆NO₆P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CGS 35066

CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively[1].

Name	CGS 35066,α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoicacid
Synonym	More Synonyms

Description	CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. A J Trapani, et al. Pharmacological properties of CGS 35066, a potent and selective endothelin-converting enzyme inhibitor, in conscious rats. J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S40-3.

Molecular Formula	C₁₆H₁₆NO₆P
Molecular Weight	349.27500
Exact Mass	349.07200
PSA	129.81000
LogP	2.69740

Gisadenafil besylate

CGS 35066

Use of CGS 35066

Names

CGS 35066 Biological Activity

Chemical & Physical Properties

Synonyms