(S)-MRTX-1719

Modify Date: 2025-08-25 11:59:47

(S)-MRTX-1719 Structure
(S)-MRTX-1719 structure
Common Name (S)-MRTX-1719
CAS Number 2630904-44-6 Molecular Weight 464.88
Density N/A Boiling Point N/A
Molecular Formula C23H18ClFN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-MRTX-1719


(S)-MRTX-1719 (example 16-7) is the S-enantiomer of MRTX-1719. (S)-MRTX-1719 is a PRMT5/MTA complex inhibitor, with an IC50 of 7070 nM[1].

 Names

Name (S)-MRTX-1719

 (S)-MRTX-1719 Biological Activity

Description (S)-MRTX-1719 (example 16-7) is the S-enantiomer of MRTX-1719. (S)-MRTX-1719 is a PRMT5/MTA complex inhibitor, with an IC50 of 7070 nM[1].
Related Catalog
Target

IC50: 7070 nM (PRMT5/MTA complex)[1]

References

[1]. Thomas P. BOBINSKI, et al. Mta-cooperative prmt5 inhibitors. WO2021050915A1.

 Chemical & Physical Properties

Molecular Formula C23H18ClFN6O2
Molecular Weight 464.88
InChIKey BZKIOORWZAXIBA-UHFFFAOYSA-N
SMILES Cn1ncc(-c2ccc3c(=O)[nH]nc(CN)c3c2)c1-c1c(F)c(Cl)cc(OC2CC2)c1C#N
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