(12Z)-9,10-Dihydroxy-12-octadecenoic acid

Modify Date: 2024-01-08 19:00:35

(12Z)-9,10-Dihydroxy-12-octadecenoic acid Structure
(12Z)-9,10-Dihydroxy-12-octadecenoic acid structure
Common Name (12Z)-9,10-Dihydroxy-12-octadecenoic acid
CAS Number 263399-34-4 Molecular Weight 314.460
Density 1.0±0.1 g/cm3 Boiling Point 491.8±35.0 °C at 760 mmHg
Molecular Formula C18H34O4 Melting Point N/A
MSDS N/A Flash Point 265.3±22.4 °C

 Use of (12Z)-9,10-Dihydroxy-12-octadecenoic acid


(±)9,10-DiHOME is the racemate of 9,10-DiHOME. 9,10-DiHOME is a leukotoxin derivative of linoleic acid diol that has been reported to be toxic in human's tissue preparations, and is produced by inflammatory leukocytes such as neutrophils and macrophages[1].

 Names

Name (+/-)-threo-9,10-dihydroxy-12(z)-octadecenoic acid
Synonym More Synonyms

  Biological Activity

Description (±)9,10-DiHOME is the racemate of 9,10-DiHOME. 9,10-DiHOME is a leukotoxin derivative of linoleic acid diol that has been reported to be toxic in human's tissue preparations, and is produced by inflammatory leukocytes such as neutrophils and macrophages[1].
Related Catalog
References

[1]. Nieman DC, et al. Influence of pistachios on performance and exercise-induced inflammation, oxidative stress, immune dysfunction, and metabolite shifts in cyclists: a randomized, crossover trial. PLoS One. 2014;9(11):e113725. Published 2014 Nov 19.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 491.8±35.0 °C at 760 mmHg
Molecular Formula C18H34O4
Molecular Weight 314.460
Flash Point 265.3±22.4 °C
Exact Mass 314.245697
PSA 77.76000
LogP 4.14
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.493
Storage condition -20°C

 Synonyms

12-Octadecenoic acid, 9,10-dihydroxy-, (9R,10R,12Z)-
leukotoxin diol
12-Octadecenoic acid, 9,10-dihydroxy-, (12Z)-
(9R,10R,12Z)-9,10-Dihydroxy-12-octadecenoic acid
(12Z)-9,10-Dihydroxy-12-octadecenoic acid
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