263399-34-4

263399-34-4 structure

Name: (12Z)-9,10-Dihydroxy-12-octadecenoic acid
Chemical Name: (+/-)-threo-9,10-dihydroxy-12(z)-octadecenoic acid
CAS Number: 263399-34-4
Molecular Formula: C₁₈H₃₄O₄
Molecular Weight: 314.460
Create Date: 2016-01-23 03:28:38
Modify Date: 2025-08-25 18:20:46
(±)9,10-DiHOME is the racemate of 9,10-DiHOME. 9,10-DiHOME is a leukotoxin derivative of linoleic acid diol that has been reported to be toxic in human's tissue preparations, and is produced by inflammatory leukocytes such as neutrophils and macrophages[1].

Name	(+/-)-threo-9,10-dihydroxy-12(z)-octadecenoic acid
Synonyms	12-Octadecenoic acid, 9,10-dihydroxy-, (9R,10R,12Z)- leukotoxin diol 12-Octadecenoic acid, 9,10-dihydroxy-, (12Z)- (9R,10R,12Z)-9,10-Dihydroxy-12-octadecenoic acid (12Z)-9,10-Dihydroxy-12-octadecenoic acid

Description	(±)9,10-DiHOME is the racemate of 9,10-DiHOME. 9,10-DiHOME is a leukotoxin derivative of linoleic acid diol that has been reported to be toxic in human's tissue preparations, and is produced by inflammatory leukocytes such as neutrophils and macrophages[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Nieman DC, et al. Influence of pistachios on performance and exercise-induced inflammation, oxidative stress, immune dysfunction, and metabolite shifts in cyclists: a randomized, crossover trial. PLoS One. 2014;9(11):e113725. Published 2014 Nov 19.