4,4'-Dithiodipyridine
4,4'-Dithiodipyridine structure
|
Common Name | 4,4'-Dithiodipyridine | ||
|---|---|---|---|---|
| CAS Number | 2645-22-9 | Molecular Weight | 220.31400 | |
| Density | 1.34 g/cm3 | Boiling Point | 356.1ºC at 760 mmHg | |
| Molecular Formula | C10H8N2S2 | Melting Point | 76-78 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 169.2ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4,4'-dipyridyl disulfide |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.34 g/cm3 |
|---|---|
| Boiling Point | 356.1ºC at 760 mmHg |
| Melting Point | 76-78 °C(lit.) |
| Molecular Formula | C10H8N2S2 |
| Molecular Weight | 220.31400 |
| Flash Point | 169.2ºC |
| Exact Mass | 220.01300 |
| PSA | 76.38000 |
| LogP | 3.27600 |
| Vapour Pressure | 6.14E-05mmHg at 25°C |
| Index of Refraction | 1.693 |
| InChIKey | UHBAPGWWRFVTFS-UHFFFAOYSA-N |
| SMILES | c1cc(SSc2ccncc2)ccn1 |
| Storage condition | 0-6°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~93%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Journal of Chemical Research - Part S, , # 11 p. 547 - 549 |
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~%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Canadian Journal of Chemistry, , vol. 68, # 9 p. 1482 - 1489 |
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~%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Polish Journal of Chemistry, , vol. 66, # 5 p. 787 - 790 |
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~%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Journal of the Chemical Society, , p. 1853 Anales de la Real Sociedad Espanola de Fisica y Quimica, , vol. 54, p. 383,386 |
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~%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Chemische Berichte, , vol. 54, p. 1359 |
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~%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 1 p. 31 - 36 |
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~%
4,4'-Dithiodipy... CAS#:2645-22-9 |
| Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 4 p. 441 - 447 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 7 | |
CAS#:26157-58-4
CAS#:1892-29-1
CAS#:65938-88-7
CAS#:134479-04-2
CAS#:501422-69-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Oxidative stress and lipid peroxidation are upstream of amyloid pathology.
Neurobiol. Dis. 84 , 109-19, (2015) Oxidative stress is a common feature of the aging process and of many neurodegenerative disorders, including Alzheimer's disease. Understanding the direct causative relationship between oxidative stre... |
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Molecularly imprinted tunable binding sites based on conjugated prosthetic groups and ion-paired cofactors.
J. Am. Chem. Soc. 131(25) , 8833-8, (2009) A molecular imprinting technique was applied to the construction of prosthetic group-coupled tunable binding cavities for bisphenol A (BPA). A novel template molecule, with a structure consisting of B... |
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Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.
Anal. Bioanal. Chem 373(4-5) , 266-76, (2002) Since its introduction in 1959, Ellman's reagent (5,5'-dithio-bis(2-nitrobenzoic acid)) has been the favorite reagent for spectrophotometric measurement of protein sulfhydryls. Meanwhile however, evid... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: Induction of S-nitrosylation of TRPC5 in HEK cells assessed as increase in Ca2+ level...
Source: ChEMBL
Target: Short transient receptor potential channel 5
External Id: CHEMBL1252889
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4,4′-Dipyridyl disulfide |
| Pyridine,4,4'-dithiobis |
| 4,4'-Dithiodipyridine |
| 4-aldrithiol |
| Di(4-pyridinyl) disulfide |
| 4,4'-bispyridinyl disufide |
| 4,4‘-Dithiodipyridine |
| Aldrithiol(TM)-4 |
| 1,2-Di(pyridin-4-yl)disulfane |
| 4-(pyridin-4-yldisulfanyl)pyridine |
| Aldrithiol 4 |
| 4,4'-Dipyridyl disuldide |
| EINECS 220-158-6 |
| 4,4'-Dipyridyl disulfide |
| Aldrithiol™-4 |
| MFCD00006423 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of 4,4'-dipyridyl disulfide? |
| A: InChIKey of 4,4'-dipyridyl disulfide is UHBAPGWWRFVTFS-UHFFFAOYSA-N. |
| Q: What is the English name of 4,4'-dipyridyl disulfide? |
| A: The English name of 4,4'-dipyridyl disulfide is 4,4'-dipyridyl disulfide. |
| Q: What is the safety information for 4,4'-dipyridyl disulfide? |
| A: Safety information for 4,4'-dipyridyl disulfide: S26-S36. |
| Q: What are the storage conditions for 4,4'-dipyridyl disulfide? |
| A: Storage conditions for 4,4'-dipyridyl disulfide: 0-6°C. |
| Q: What is the CAS number of 4,4'-dipyridyl disulfide? |
| A: CAS number of 4,4'-dipyridyl disulfide is 2645-22-9. |
| Q: What are the downstream products of 4,4'-dipyridyl disulfide? |
| A: Related downstream products(CAS) of 4,4'-dipyridyl disulfide: 4556-23-4;26157-58-4;1892-29-1;5402-20-0;65938-88-7;134479-04-2;501422-69-1. |
| Q: What is the polar surface area (PSA) of 4,4'-dipyridyl disulfide? |
| A: Polar surface area (PSA) of 4,4'-dipyridyl disulfide is 76.38000. |
| Q: What is the boiling point of 4,4'-dipyridyl disulfide? |
| A: Boiling point of 4,4'-dipyridyl disulfide is 356.1ºC at 760 mmHg. |
| Q: What English synonyms does 4,4'-dipyridyl disulfide have? |
| A: English synonyms of 4,4'-dipyridyl disulfide: 4,4′-Dipyridyl disulfide, Pyridine,4,4'-dithiobis, 4,4'-Dithiodipyridine, 4-aldrithiol, Di(4-pyridinyl) disulfide, 4,4'-bispyridinyl disufide, 4,4‘-Dithiodipyridine, Aldrithiol(TM)-4, 1,2-Di(pyridin-4-yl)disulfane, 4-(pyridin-4-yldisulfanyl)pyridine, Aldrithiol 4, 4,4'-Dipyridyl disuldide, EINECS 220-158-6, 4,4'-Dipyridyl disulfide, Aldrithiol™-4, MFCD00006423. |
| Q: What is the LogP of 4,4'-dipyridyl disulfide? |
| A: LogP of 4,4'-dipyridyl disulfide is 3.27600. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |