4,4'-Dithiodipyridine

Modify Date: 2025-08-25 19:59:42

4,4'-Dithiodipyridine Structure
4,4'-Dithiodipyridine structure
Common Name 4,4'-Dithiodipyridine
CAS Number 2645-22-9 Molecular Weight 220.31400
Density 1.34 g/cm3 Boiling Point 356.1ºC at 760 mmHg
Molecular Formula C10H8N2S2 Melting Point 76-78 °C(lit.)
MSDS Chinese USA Flash Point 169.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4,4'-dipyridyl disulfide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.34 g/cm3
Boiling Point 356.1ºC at 760 mmHg
Melting Point 76-78 °C(lit.)
Molecular Formula C10H8N2S2
Molecular Weight 220.31400
Flash Point 169.2ºC
Exact Mass 220.01300
PSA 76.38000
LogP 3.27600
Vapour Pressure 6.14E-05mmHg at 25°C
Index of Refraction 1.693
InChIKey UHBAPGWWRFVTFS-UHFFFAOYSA-N
SMILES c1cc(SSc2ccncc2)ccn1
Storage condition 0-6°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

~93%

4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Journal of Chemical Research - Part S, , # 11 p. 547 - 549

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4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Canadian Journal of Chemistry, , vol. 68, # 9 p. 1482 - 1489

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4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Polish Journal of Chemistry, , vol. 66, # 5 p. 787 - 790

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4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Journal of the Chemical Society, , p. 1853 Anales de la Real Sociedad Espanola de Fisica y Quimica, , vol. 54, p. 383,386

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4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Chemische Berichte, , vol. 54, p. 1359

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4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 1 p. 31 - 36

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4,4'-Dithiodipyridine Structure

4,4'-Dithiodipy...

CAS#:2645-22-9

Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 4 p. 441 - 447

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles31

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Molecularly imprinted tunable binding sites based on conjugated prosthetic groups and ion-paired cofactors.

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A molecular imprinting technique was applied to the construction of prosthetic group-coupled tunable binding cavities for bisphenol A (BPA). A novel template molecule, with a structure consisting of B...

Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.

Anal. Bioanal. Chem 373(4-5) , 266-76, (2002)

Since its introduction in 1959, Ellman's reagent (5,5'-dithio-bis(2-nitrobenzoic acid)) has been the favorite reagent for spectrophotometric measurement of protein sulfhydryls. Meanwhile however, evid...

 4,4'-DithiodipyridineBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: Induction of S-nitrosylation of TRPC5 in HEK cells assessed as increase in Ca2+ level...
Source: ChEMBL
Target: Short transient receptor potential channel 5
External Id: CHEMBL1252889
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 Synonyms

4,4′-Dipyridyl disulfide
Pyridine,4,4'-dithiobis
4,4'-Dithiodipyridine
4-aldrithiol
Di(4-pyridinyl) disulfide
4,4'-bispyridinyl disufide
4,4‘-Dithiodipyridine
Aldrithiol(TM)-4
1,2-Di(pyridin-4-yl)disulfane
4-(pyridin-4-yldisulfanyl)pyridine
Aldrithiol 4
4,4'-Dipyridyl disuldide
EINECS 220-158-6
4,4'-Dipyridyl disulfide
Aldrithiol™-4
MFCD00006423
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