D-Sedoheptulose 7-phosphate

Modify Date: 2024-01-06 13:33:03

D-Sedoheptulose 7-phosphate Structure
D-Sedoheptulose 7-phosphate structure
Common Name D-Sedoheptulose 7-phosphate
CAS Number 2646-35-7 Molecular Weight 425.47300
Density 1.862g/cm3 Boiling Point 751.4ºC at 760mmHg
Molecular Formula C7H15O10P Melting Point N/A
MSDS N/A Flash Point 408.3ºC

 Use of D-Sedoheptulose 7-phosphate


D-Sedoheptulose 7-phosphate is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose 7-phosphate can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds [1].

 Names

Name sedoheptulose 7-phosphate
Synonym More Synonyms

 D-Sedoheptulose 7-phosphate Biological Activity

Description D-Sedoheptulose 7-phosphate is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose 7-phosphate can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds [1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Sedoheptulose 7-phosphate can be converted to ADP-l-glycero-β-d-manno-heptose by SepB, SepL, and SepC, it involves in ADP-sugar in microbial natural product biosynthesis[1]. SepB is an S-7-P isomerase, SepL involves in the biosynthesis of heptoses of the core region of E. coli LPS, and they catalyze a four-reaction relay converting S-7-P into ADP-d-glycero-β-d-manno-heptose [1]. Septacidin and its analogs are potential anticancer and pain-relief agents[1]. Hygromycin B is an anthelmintic agent practically used in swine and poultry farming[1].
References

[1]. Tang W, et al. d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B.Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2818-2823.

 Chemical & Physical Properties

Density 1.862g/cm3
Boiling Point 751.4ºC at 760mmHg
Molecular Formula C7H15O10P
Molecular Weight 425.47300
Flash Point 408.3ºC
Exact Mass 425.93000
PSA 192.61000
Vapour Pressure 4.61E-26mmHg at 25°C
Index of Refraction 1.605

 Synonyms

Sedoheptulose-7-phosphate
O7-phosphono-D-altro-[2]heptulose
D-sedoheptulose-7-phosphate
(2,3,4,5,7-pentahydroxy-6-oxo-heptoxy)phosphonic acid